- Protects healthy cells from oxidative stress.
- Reduces damage caused by free radicals.
- Helps reverse damage caused by chronic stress.
- Enhances energy metabolism and cellular respiration.
- Helps prevent oxidation-related damage to hormone and immune processes.
- Contributes to heart and brain health.
- Helps maintain smooth and firm skin.
- Highly bioavailable forms of essential nutrients.
- Therapeutic quantities of Coenzyme Q10, Alpha-Lipoic acid, and grape seed extract.
- The quality of raw materials in BioMatrix™ Support Anti-Ox is exceptional. †
Oxidative stress occurs when the production of free radicals and other oxidative molecules exceeds the capacity of the body's antioxidant defenses. Cells react with oxygen as part of energy metabolism. As a consequence of these normal processes, free radicals - atoms or molecules which have unpaired electrons - are produced. Free radicals are very unstable and react with other compounds, to capture a needed electron to gain stability. Generally, free radicals attack the nearest stable molecule, stealing its electron. When that molecule loses its electron, it becomes a free radical itself, beginning a chain reaction. Once the process is started, it can cascade, resulting in the disruption of healthy cells.
Free radicals are produced normally in the body during metabolism and also as a result of chronic stress. Also, living in a world that is far from clean and pure, the body must cope with the daily challenges of a toxic world. A strong and effective dietary supplement can overcome the unavoidable, harmful effects of our environment. For patients with pronounced oxidative stress (revealed through laboratory markers such as lipid peroxides) higher dosages can be used to reverse damage and resist future problems.
Support Anti-Ox is a potent antioxidant formula with a synergistic blend of nutrients formulated to protect every cell in the body from free radical damage. When we set out to create an antioxidant formula, we had questions for prominent manufacturers about their formulas: “Why are the levels of CoQ10 so low? Why is there such a small amount of Alpha Lipoic acid and grape seed extract? Why don’t you use natural carotenoids?” To these questions and others he received a consistent response: “It would be too expensive. We compete with health food stores.” Knowing that patients with pronounced oxidative stress require high levels of certain nutrients, we took the position that it is costly to use cheap antioxidants – he formulated Support Anti-Ox to provide robust antioxidant support.
A Single Antioxidant Product: Better Absorption and Improved Compliance
It would take multiple multi-nutrient antioxidant products to achieve the combined therapeutic levels available in Support Anti-Ox. This popular product is the result of the study of hundreds of patients and their oxidative stress lab results. Using the data yielded by this study, we were able to synthesize a single product that incorporates antioxidants proven successful in fighting oxidative stress. Besides classic free radical scavengers and the finest antioxidant substances in their ideal forms, Support Anti-Ox also includes pure-form bioflavonoids, which are necessary for tissue healing and reducing the inflammation that is associated with excessive oxidative stress. Support Anti-Ox is an ideal daily supplement also used by doctors in therapeutic protocols that address advanced oxidative stress.
Two Capsules of Support Anti-Ox Contain:
Vitamin A ( as 10000 IU Betatene® natural mixed carotenoids and 2000 IU Vitamin A Palmitate) - 12,000 IU
A free radical scavenger, vitamin A's roles in health and physiology are numerous. The blend of Betatene® natural mixed carotenoids and Vitamin A Palmitate in Support Anti-Ox is balanced to provide easy absorption and improved metabolism. Many patients have a problem converting beta carotene into vitamin A so the Vitamin A precursor Vitamin A Palmitate is used. Betatene® natural mixed carotenoids contain several carotenoids derived from Dunaliella salina algae that are broadly accepted by the scientific community.1,2, 3
Vitamin C (342 mg as Calcium Ascorbate, 342 mg as Magnesium Ascorbate, 16 mg as Ascorbyl Palmitate) - 700 mg
Vitamin C is another important free radical scavenger. The 700 mg in Support Anti-Ox is comprised of three different forms, each serving particular metabolic mechanisms to best support the formula's other components. Importantly Vitamin C combats the peroxidation of lipids, which has been linked to degeneration and the aging process. One study of elderly people found that 400 mg of vitamin C per day (for a one-year period) reduced serum lipid peroxide levels significantly. 4, 5
Calcium (as Calcium Ascorbate) - 48 mg
The calcium portion of the Calcium Ascorbate used primarily to provide quality Vitamin C.
Vitamin E (as d-alpha tocopherol acid succinate) - 400 IU
Another essential free radical scavenger, vitamin E's antioxidant properties are well known and proven. The vitamin E in Support Anti-Ox comes in the form of d-alpha tocopherol acid succinate to guarantee the best possible absorption given the formula's other ingredients. The succinate form of vitamin E appears to benefit areas of the tissues that are unavailable to the other forms. For this reason, there is a tendency to regard alpha-tocopherol succinate as a distinctly unique and beneficial compound. Unlike other forms of vitamin E, alpha-tocopherol succinate appears to have longer half-life in the body, and does not interfere with vitamin A absorption 6, 7.
Magnesium (as Magnesium Ascorbate) - 26 mg
The magnesium portion of the Magnesium Ascorbate used primarily to provide quality Vitamin C.
Selenium (as Selenium Chelate) - 75 mcg
One of the most well-known and proven antioxidants, selenium activates the antioxidant enzyme glutathione peroxidase. Long known as a substance synergistic with vitamin E, it is provided here in a chelate to ensure optimal absorption. 8,9
Lemon Pure Form Bioflavonoid Complex - 100 mg
This bioflavonoid complex assists vitamin C in keeping collagen healthy, is essential for proper absorption of vitamin C, and prevents vitamin C from being destroyed by oxidation. Bioflavonoids are important for supporting vitamin C's antioxidant properties and reversing the damage caused by oxidation.10,11
Alpha-Lipoic Acid - 100 mcg
The body needs Alpha-Lipoic Acid (ALA) to produce energy. It plays a crucial role in the mitochondria, the energy-producing structures in cells. The body produces enough ALA for these basic functions. This compound acts as an antioxidant only when there is an excess of it (and it is in a state that is available to the cells). There is little free ALA circulating in the body, unless acquired through supplementation. Foods contain miniscule amounts of it. ALA is a unique antioxidant due to its versatility - it helps deactivate an wide array of cell-damaging free radicals in many bodily systems. Support Anti-Ox provides therapeutic levels to serve the goals of discerning practitioners.12,13,14
Activin®; Dried ethanol extract of grape seed (Vitis vinifera) - 75 mg
Antioxidants, called oligomeric proanthocyanidins (OPCs), found in grape seed extract are significantly more potent than vitamins A, C, and E. Activin® grape seed extract is 2.4 times more potent than vitamin E, 4.8 times more potent than vitamin C and 7.3 times more potent than beta-carotene. Activin or grape seed proanthocyanidins are sustained-release antioxidants, remaining in the body up to 7-10 days following ingestion. 15,16
Coenzyme Q10 - 50 mg
CoQ10's key role is to produce adenosine triphosphate (ATP), needed for energy production in every cell of the body, and is used readily for cardiovascular support. Secondarily, CoQ10 functions as a powerful antioxidant. The antioxidant nature of CoQ10 is derived from its energy carrier function. As an energy carrier, the CoQ10 molecule continuously goes through an oxidation-reduction cycle. As it accepts electrons, it becomes reduced. As it gives up electrons, it becomes oxidized. In its reduced form, the CoQ10 molecule holds electrons rather loosely, so this Coenzyme Q molecule will easily give up one or both electrons and thus act as an antioxidant. The amount of CoQ10 in Support Anti-Ox is sufficient to make a powerful impact unlike most antioxidant formulas which minimize the use of this expensive nutrient.17,18, 19
Rutin - 5 mg
Rutin attaches to the iron ion Fe2+, preventing it from binding to hydrogen peroxide and creating a highly reactive free radical. Rutin is a natural bioflavonoid extracted from fruits of the Fava D'Anta tree native to Brazil. 20, 21
Two capsules a day for maintenance in the absence of elevated lipid peroxides or other clinical indicators of oxidative stress. Always take Support Anti-Ox with meals.
Individualized dosages can be further refined with data provided by testing lipid peroxide levels .
Levy. Beta-carotene affects antioxidant status in non-insulin dependent. Pathophysiology. 1999;6(3):157-161.
Sies H., Stahl W. Vitamins E and C, beta -carotene, and other carotenoids as antioxidants. Am. J. Clin. Nutr. 1995; 62:1315S-1321S
Stahl W; Schwarz W; Sies H;. Human serum concentrations of all-trans beta- and alpha-carotene but not 9-cis beta-carotene increase upon ingestion of a natural isomer mixture obtained from Dunaliella salina (Betatene). J Nutr. 123: 847-851.
Zan T, Tao J, Tang RC, Liu YC, Liu Y, Huang B, Zhou JY, Wu MH, Liu HL. Effect of vitamin C antioxidative protection on human red blood cells. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2005 Dec;13(6):1106-8.
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Vinson JA, Bose P. Comparative bioavailability to humans of ascorbic acid alone or in a citrus extract. Am J Clin Nutr 1988;48:601-4.
Kuo SM. Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells. Cancer Lett 1996;110:41-8.
Kramer K, Packer L. R-alpha-lipoic acid. In: Kramer K, Hoppe P, Packer L, eds. Nutraceuticals in Health and Disease Prevention. New York: Marcel Dekker, Inc.; 2001:129-164.
Packer L. alpha-Lipoic acid: a metabolic antioxidant which regulates NF-kappa B signal transduction and protects against oxidative injury. Drug Metab Rev. 1998;30(2):245-275.
Suh JH, Shigeno ET, Morrow JD, et al. Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid. Faseb J. 2001;15(3):700-706.
Krohn RL, In Vitro and In Vivo Free Radical Scavenging Abilities of a Novel Grape Seed Proanthocyanidin Extract and Selected Antioxidants, The 1997 Midwest Student Medical Research Forum XXVIII, Omaha, NE, February 21-22, 1997.
Scheckenbach RP, Comparative In Vitro and In Vivo Free Radical Scavenging Abilities of Grape Seed Proanthocyanidins and Selected Antioxidants, International Conference on Stress Adaptation, Prophylaxis and Treatment, Calcutta, India, January 10-12, 1998.
Crane FL. Biochemical functions of coenzyme Q10. J Am Coll Nutr. 2001;20(6):591-598.
Mohr D, Bowry VW, Stocker R. Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim Biophys Acta. 1992;1126(3):247-254.
Alho H, Lonnrot K. Coenzyme Q supplementation and longevity. In: Kagan VE, Quinn PJ, eds. Coenzyme Q: Molecular Mechanisms in Health and Disease. Boca Raton: CRC Press; 2001:371-380.
Grinberg LN, Rachmilewitz EA, Newmark H. Protective effects of rutin against hemoglobin oxidation. Biochem Pharmacol. 1994 Aug 17; 48(4): 643-9.
Webster, R.P., et al., Protective effect of rutin, a flavonol glycoside, on the carcinogen-induced DNA damage and repair enzymes in rats. Cancer Lett. 109, 185-191, (1996).